TMS Therapy and How it Works

NeuroStar TMS Therapy is a safe, non-invasive treatment for depression that uses a highly focused, pulsed magnetic field to stimulate function in targeted brain regions that control mood and depression. It is available by prescription only and it is performed under the supervision of a Psychiatrist. It does not require anesthesia or sedation and patients remain awake and alert throughout the procedure. NeuroStar TMS Therapy is a 37-minute outpatient that is administered daily for four to six weeks (20-30 treatments).

NeuroStar TMS System

NeuroStar TMS System
The NeuroStar TMS Therapy® system is the first and only non-systemic and non-invasive TMS system for the treatment of depression. It was recently cleared (October 2008) by the U.S. Food and Drug Administration (FDA) for the treatment of Major Depressive Disorder in adult patients who have failed to achieve satisfactory improvement from prior antidepressant medication.*

How it Works

How Magnetic Pulses Work
The objective of TMS Therapy is to stimulate (or activate) brain cells, called neurons. The unique nature of magnetic fields allows them to pass through the skull and into the cortex without being distorted in any way. This facilitates a very focal type of stimulation, minimizing stimulation of brain tissue not involved in mood.

Limbic System
The short pulses of magnetic energy produced by NeuroStar® TMS Therapy System are aimed by the treating clinician at the left prefrontal cortex (PFC). This promotes changes in the PFC, as well as in deeper brain structures, like the limbic system, regions involved in mood regulation.
Neurons ActivatedOnce inside the brain, the dynamic (rapidly changing) nature of the magnetic pulses induces electrical charges to flow. The amount of electricity created in the brain is very small, and cannot be felt by the patient. When in the correct orientation relative to brain cells (neurons), these very small electric charges can cause the neurons to fire or become active. This leads to release of brain chemicals or neurotransmitters like serotonin, norepinephrine, and dopamine.
(neuron network)
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Clinical Depression is a medical disorder characterized by feelings of sadness, hopelessness, pessimism, guilt, and a general loss of interest in life, combined with a sense of reduced emotional well-being and low energy. People with depression also tend to have disturbed sleep, reduced appetite and may even feel suicidal.